Article
High concordance of EGFR mutation status between histologic and corresponding cytologic specimens of lung adenocarcinomas.
Cancer cytopathology - 1 Jun 2013
Sun Ping-Li, Jin Yan, Kim Hyojin, Lee Choon-Taek, Jheon Sanghoon, Chung Jin-Haeng
Abstract excerpt
BACKGROUND: Activating mutations in the epidermal growth factor receptor (EGFR) in non-small cell lung carcinoma (NSCLC) are associated significantly with responsiveness to EGFR tyrosine kinase inhibitors. The objective of this study was to investigate the suitability of cytologic specimens for assessing EGFR mutations in lung adenocarcinomas. METHODS: Sixty paired histologic and cytologic specimens of lung...
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