Article
MassARRAY, pyrosequencing, and PNA clamping for EGFR mutation detection in lung cancer tissue and cytological samples: a multicenter study.
Journal of cancer research and clinical oncology - 1 Oct 2016
Min Kyueng-Whan, Kim Wan-Seop, Jang Se Jin, Choi Yoo Duk, Chang Sunhee, Jung Soon Hee, Kim Lucia, Roh Mee-Sook, Lee Choong Sik, Shim Jung Weon, Kim Mi Jin, Lee Geon Kook
Abstract excerpt
BACKGROUND: Testing for epidermal growth factor receptor (EGFR) mutation is an important process in the therapeutic plan of patients with lung cancer. Recently, MassARRAY, based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, has been shown to be a useful method for somatic mutation analysis with pyrosequencing and peptide nucleic acid clamping (PNAc). METHODS: A total of 107...
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