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Article

EGFR mutations are detected comparably in cytologic and surgical pathology specimens of nonsmall cell lung cancer.

Cancer - 25 Feb 2009

Smouse Jason H, Cibas Edmund S, Jänne Pasi A, Joshi Victoria A, Zou Kelly H, Lindeman Neal I

Abstract excerpt

BACKGROUND: Somatic mutations in the epidermal growth factor receptor (EGFR) are present in approximately 10% of nonsmall cell lung cancers, and higher in never-smokers, women, and Asians. Small in-frame deletions in exon 19 ( approximately 45%) and L858R mutation in exon 21 ( approximately 40%) predict response to treatment with tyrosine kinase inhibitors, whereas some others herald resistance. Direct sequencing...

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Source

Identifiers

PMID: 19347832
DOI: 10.1002/cncy.20011

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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