Article
Performance of EGFR mutant-specific antibodies in different cytological preparations: a validation study.
Cytopathology : official journal of the British Society for Clinical Cytology - 1 Apr 2015
Bellevicine C, Bianco A, Malapelle U, De Luca C, Vigliar E, Cacciola N A, Pallante P, Troncone G
Abstract excerpt
OBJECTIVES: Molecular testing for epidermal growth factor receptor (EGFR) mutations is required to select the most appropriate treatment for advanced-stage non-small cell lung cancer (NSCLC). In routine practice, cytological samples are often the only specimens available for testing. When the number of neoplastic cells is large, DNA-based assays are the gold standard. When cytological samples contain only a few...
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