Article
The 11q13-q14 amplicon: clinicopathological correlations and potential drivers.
Genes, chromosomes & cancer - 1 Apr 2013
Wilkerson Paul M, Reis-Filho Jorge S
Abstract excerpt
Amplification at 11q13-q14 is a common event in cancers from multiple anatomical sites. This complex amplicon has multiple cores and several genes have been put forward as potential "drivers." In this review, based on the technical advancements of the last decade, which resulted in methods allowing for a deeper genomic and functional genomic characterization of amplicons and their drivers, we discuss the current...
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