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Article

MED12 mutations occurring in benign and malignant mammalian smooth muscle tumors.

Genes, chromosomes & cancer - 1 Mar 2013

Markowski Dominique Nadine, Huhle Sonja, Nimzyk Rolf, Stenman Göran, Löning Thomas, Bullerdiek Jörn

Abstract excerpt

Mutations of the mediator subcomplex 12 gene (MED12) recently have been described in a large group of uterine leiomyomas (UL) but only in a single malignant uterine smooth muscle tumor. To further address the occurrence of fibroid-type MED12 mutations in smooth muscle tumors, we have analyzed samples from 34 leiomyosarcomas (LMS), 21 UL, two extrauterine leiomyomas (EL), and 10 canine genital leiomyomas for the...

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Source

Identifiers

PMID: 23225304
DOI: 10.1002/gcc.22029

Genes

MED12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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