Article
Identification of the NF-κB activating protein-like locus as a risk locus for rheumatoid arthritis.
Annals of the rheumatic diseases - 1 Jul 2013
Xie Gang, Lu Yue, Sun Ye, Zhang Steven Shiyang, Keystone Edward Clark, Gregersen Peter K, Plenge Robert M, Amos Christopher I, Siminovitch Katherine A
Abstract excerpt
OBJECTIVE: To fine-map the NF-κB activating protein-like (NKAPL) locus identified in a prior genome-wide study as a possible rheumatoid arthritis (RA) risk locus and thereby delineate additional variants with stronger and/or independent disease association. METHODS: Genotypes for 101 SNPs across the NKAPL locus on chromosome 6p22.1 were obtained on 1368 Canadian RA cases and 1471 controls. Single marker...
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