Article
Investigating the GWAS-Implicated Loci for Rheumatoid Arthritis in the Pakistani Population.
Disease markers - 1 Jan 2020
Aslam Muhammad Muaaz, John Peter, Fan Kang-Hsien, Bhatti Attya, Aziz Wajahat, Ahmed Bashir, Feingold Eleanor, Demirci F Yesim, Kamboh M Ilyas
Abstract excerpt
Rheumatoid arthritis (RA) is a complex and multifactorial autoimmune disorder with the involvement of multiple genetic and environmental factors. Genome-wide association studies (GWAS) have identified more than 50 RA genetic loci in European populations. Given the anticipated overlap of RA-relevant genes and pathways across different ethnic groups, we sought to replicate 58 GWAS-implicated SNPs reported in...
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