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Article

Decreased T-cell repertoire diversity in sepsis: a preliminary study.

Critical care medicine - 1 Jan 2013

Venet Fabienne, Filipe-Santos Orchidée, Lepape Alain, Malcus Christophe, Poitevin-Later Françoise, Grives Audrey, Plantier Nadia, Pasqual Nicolas, Monneret Guillaume

Abstract excerpt

OBJECTIVE: Septic syndromes are the leading causes of mortality in intensive care units. In patients, the occurrence of sepsis-induced immune suppression is associated with delayed mortality, although the exact role of lymphocyte dysfunctions is not well established. The objective of this study was to investigate T-cell receptor diversity, an important feature of T-cell response, in patients with septic shock....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Antigen, T-Cell, alpha-beta

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Source

Identifiers

PMID: 23222261
DOI: 10.1097/CCM.0b013e3182657948

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TRB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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