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Article

RAD52 variants predict platinum resistance and prognosis of cervical cancer.

PloS one - 1 Jan 2012

Shi Ting-Yan, Yang Gong, Tu Xiao-Yu, Yang Jing-Min, Qian Ji, Wu Xiao-Hua, Zhou Xiao-Yan, Cheng Xi, Wei Qingyi

Abstract excerpt

RAD52 is an important but not well characterized homologous recombination repair gene that can bind to single-stranded DNA ends and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. To evaluate the role of RAD52 variants in the response of tumor cells to platinum agents, we investigated their associations with platinum resistance and prognosis in cervical cancer patients....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Organoplatinum Compounds

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Source

Open in PubMed Open full text

Identifiers

PMID: 23209746
DOI: 10.1371/journal.pone.0050461
PMCID: PMC3510183

Genes

RAD52

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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