Article
The Cell Cycle Checkpoint Gene, RAD17 rs1045051, Is Associated with Prostate Cancer Risk.
Acta medica Okayama - 1 Aug 2021
Sun Jingkai, Lin Wenfeng, Wang Qixu, Sakai Akiko, Xue Ruizhi, Watanabe Masami, Liu Chunxiao, Sadahira Takuya, Nasu Yasutomo, Xu Abai, Huang Peng
Abstract excerpt
Human RAD17, as an agonist of checkpoint signaling, plays an essential role in mediating DNA damage. This hospital-based case-control study aimed to explore the association between RAD17 rs1045051, a missense sin-gle nucleotide polymorphism (SNP), and prostate cancer risk. Subjects were 358 prostate cancer patients and 314 cancer-free urology patients undergoing treatment at the Zhujiang Hospital of Southern...
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