Article
Association of a functional RAD52 genetic variant locating in a miRNA binding site with risk of HBV-related hepatocellular carcinoma.
Molecular carcinogenesis - 1 Sept 2015
Li Ziqiang, Guo Yuan, Zhou Liqing, Ge Yunxia, Wei Lili, Li Lichao, Zhou Changchun, Wei Jinyu, Yuan Qipeng, Li Jie, Yang Ming
Abstract excerpt
As an important member in homologous recombination repair, RAD52 plays a crucial part in maintaining genomic stability and prevent carcinogenesis. Several cancer susceptibility RAD52 single nucleotide polymorphisms (SNPs) have been identified previously. However, little or nothing has been known about the RAD52 SNPs and their functional significance in hepatitis B viruses (HBV)-related hepatocellular carcinoma...
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