Article
Nucleotide Excision Repair Gene ERCC2 and ERCC5 Variants Increase Risk of Uterine Cervical Cancer.
Cancer research and treatment - 1 Apr 2016
Joo Jungnam, Yoon Kyong-Ah, Hayashi Tomonori, Kong Sun-Young, Shin Hye-Jin, Park Boram, Kim Young Min, Hwang Sang-Hyun, Kim Jeongseon, Shin Aesun, Kim Joo-Young
Abstract excerpt
PURPOSE: Defects in the DNA damage repair process can cause genomic instability and play an important role in cervical carcinogenesis. The purpose of this study was to analyze the association of 29 candidate single nucleotide polymorphisms (SNPs) in genes in the DNA repair pathway, TP53, and TP53BP1 with the risk of cervical cancer. MATERIALS AND METHODS: Twenty-nine SNPs in four genes in the DNA repair pathway...
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