Article
A RAD52 genetic variant located in a miRNA binding site is associated with glioma risk in Han Chinese.
Journal of neuro-oncology - 1 Oct 2014
Lu Chao, Chen Yi-Dong, Han Sichong, Wei Jinyu, Ge Yunxia, Pan Wenting, Jiang Tao, Qiu Xiao-Guang, Yang Ming
Abstract excerpt
As a crucial homologous recombination repair gene, RAD52 participates in maintenance of genomic stability and prevention of tumorigenesis. Although several cancer susceptibility RAD52 single nucleotide polymorphisms (SNPs) have been identified previously, little was known on how the RAD52 SNPs are involved in glioma development in Han Chinese. Therefore, we examined the association between five RAD52 SNPs...
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