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Article

PTK7 marks the first human developmental EMT in vitro.

PloS one - 1 Jan 2012

Chan David N, Azghadi Soheila F, Feng Jun, Lowry William E

Abstract excerpt

Epithelial to mesenchymal transitions (EMTs) are thought to be essential to generate diversity of tissues during early fetal development, but these events are essentially impossible to study at the molecular level in vivo in humans. The first EMT event that has been described morphologically in human development occurs just prior to generation of the primitive streak. Because human embryonic stem cells (hESCs)...

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Identifiers

PMID: 23209741
DOI: 10.1371/journal.pone.0050432
PMCID: PMC3508926

Genes

PTK7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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