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Downregulation of E-cadherin in pluripotent stem cells triggers partial EMT

21 Jan 2021

Abstract excerpt

Epithelial to mesenchymal transition (EMT) is a critical cellular process that has been well characterized during embryonic development and cancer metastasis and it also is implicated in several physiological and pathological events including embryonic stem cell differentiation. During early stages of differentiation, human embryonic stem cells pass through EMT where deeper morphological, molecular and...

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PMID: 33479502
DOI: 10.1038/s41598-021-81735-1

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