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Transcriptomic features of trophoblast lineage cells derived from human induced pluripotent stem cells treated with BMP 4

9 Oct 2019

Abstract excerpt

INTRODUCTION: Early development of the human placenta remains poorly understood due to the lack of proper model systems. Previous reports have demonstrated that human induced pluripotent stem cells (hiPSCs) treated with bone morphogenetic protein 4 (BMP4) can differentiate into extraembryonic tissues as useful models of the early stage of trophoblast (TB) differentiation. In our previous study, we optimized the...

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PMID: 31675487
DOI: 10.1016/j.placenta.2019.10.006

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