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Article

Generating embryonic stem cells from the inbred mouse strain DBA/2J, a model of glaucoma and other complex diseases.

PloS one - 1 Jan 2012

Reinholdt Laura G, Howell Gareth R, Czechanski Anne M, Macalinao Danilo G, Macnicoll Katharine H, Lin Chyuan-Sheng, Donahue Leah Rae, John Simon W M

Abstract excerpt

Mouse embryonic stem (ES) cells are derived from the inner cell mass of blastocyst stage embryos and are used primarily for the creation of genetically engineered strains through gene targeting. While some inbred strains of mice are permissive to the derivation of embryonic stem cell lines and are therefore easily engineered, others are nonpermissive or recalcitrant. Genetic engineering of recalcitrant strain...

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Identifiers

PMID: 23209647
DOI: 10.1371/journal.pone.0050081
PMCID: PMC3507949

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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