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Article

A Natural Occurring Mouse Model with Adgrv1 Mutation of Usher Syndrome 2C and Characterization of its Recombinant Inbred Strains.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2018

Yan Weiming, Long Pan, Chen Tao, Liu Wei, Yao Lu, Ren Ze, Li Xiangqian, Wang Jiancong, Xue Junhui, Tao Ye, Zhang Lei, Zhang Zuoming

Abstract excerpt

BACKGROUND/AIMS: Our laboratory discovered a Kunming mouse with enormous electroretinogram (ERG) defects. Its auditory brainstem response (ABR) threshold was significantly elevated and closely resembled the features of Usher syndrome (USH). This study sought to cross these USH-like mice (named KMush/ush mice) with CBA/CaJ mice to establish recombinant inbred strains and identify their phenotypes and genotypes....

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Identifiers

PMID: 29961073
DOI: 10.1159/000491068

Genes

ABR
ERG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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