Article
Tissue-specific regulation of chromatin insulator function.
PLoS genetics - 1 Jan 2012
Matzat Leah H, Dale Ryan K, Moshkovich Nellie, Lei Elissa P
Abstract excerpt
Chromatin insulators organize the genome into distinct transcriptional domains and contribute to cell type-specific chromatin organization. However, factors regulating tissue-specific insulator function have not yet been discovered. Here we identify the RNA recognition motif-containing protein Shep as a direct interactor of two individual components of the gypsy insulator complex in Drosophila. Mutation of shep...
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