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Article

Escargot restricts niche cell to stem cell conversion in the Drosophila testis.

Cell reports - 8 May 2014

Voog Justin, Sandall Sharsti L, Hime Gary R, Resende Luís Pedro F, Loza-Coll Mariano, Aslanian Aaron, Yates John R, Hunter Tony, Fuller Margaret T, Jones D Leanne

Abstract excerpt

Stem cells reside within specialized microenvironments, or niches, that control many aspects of stem cell behavior. Somatic hub cells in the Drosophila testis regulate the behavior of cyst stem cells (CySCs) and germline stem cells (GSCs) and are a primary component of the testis stem cell niche. The shutoff (shof) mutation, characterized by premature loss of GSCs and CySCs, was mapped to a locus encoding the...

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Identifiers

PMID: 24794442
DOI: 10.1016/j.celrep.2014.04.025
PMCID: PMC4128242

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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