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Article

HIV-1 dynamics and coreceptor usage in Maraviroc-treated patients with ongoing replication.

Antimicrobial agents and chemotherapy - 1 Feb 2013

Recordon-Pinson P, Raymond S, Bellecave P, Marcelin A G, Soulie C, Descamps D, Calvez V, Harrigan P R, Fleury H, Izopet J, Masquelier B

Abstract excerpt

There is evidence that HIV-1 evolution under maraviroc (MVC) pressure can lead to the selection of either X4-tropic variants and/or R5-tropic, MVC-resistant isolates. However, the viral dynamics of HIV-1 variants in patients with virological failure (VF) on MVC-containing regimens remain poorly studied. Here, we investigated the V3 loop evolution of HIV-1 on MVC in relation to coreceptor usage and the nature of...

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Identifiers

PMID: 23208718
DOI: 10.1128/AAC.02159-12
PMCID: PMC3553713

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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