Article
The major circadian pacemaker ARNT-like protein-1 (BMAL1) is associated with susceptibility to gestational diabetes mellitus.
Diabetes research and clinical practice - 1 Feb 2013
Pappa Kalliopi I, Gazouli Maria, Anastasiou Eleni, Iliodromiti Zoe, Antsaklis Aristides, Anagnou Nicholas P
Abstract excerpt
AIMS: Recently a relationship between circadian clock function and the risk for type 2 diabetes (T2D) has been shown. BMAL1 is a key component of the mammalian molecular clock. Two SNPs in the BMAL1 gene have been identified to confer T2D susceptibility. In the present study we investigated for the first time the association between the BMAL1 gene and the risk for GDM, in a Greek population. METHODS: We studied...
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