Article
The Q192R polymorphism of the paraoxonase-1 (PON1) gene is associated with susceptibility to gestational diabetes mellitus in the Greek population.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Aug 2017
Pappa Kalliopi I, Gazouli Maria, Anastasiou Eleni, Loutradis Dimitrios, Anagnou Nicholas P
Abstract excerpt
A key factor protecting from oxidative stress in gestational diabetes mellitus (GDM) and in type 2 diabetes (T2D) is paraoxonase-1 (PON1). Inconclusive and limited data exist regarding the effect of a coding polymorphism (Q192R) of the PON1 gene in conferring susceptibility to both states. In the present study, we investigated the association between the PON1 gene and the risk for GDM in the Greek population and...
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