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Association of BMAL1 clock gene polymorphisms with fasting glucose in children.

Pediatric research - 1 Aug 2023

Yang Yi-De, Zeng Yuan, Li Jian, Zhou Jun-Hua, He Quan-Yuan, Zheng Chan-Juan, Reichetzeder Christoph, Krämer Bernhard K, Hocher Berthold

Abstract excerpt

BACKGROUND: The brain and muscle Arnt-like protein-1 (BMAL1) gene is an important circadian clock gene and previous studies have found that certain polymorphisms are associated with type 2 diabetes in adults. However, it remains unknown if such polymorphisms can affect fasting glucose in children and if other factors modify the associations. METHODS: A school-based cross-sectional study with 947 Chinese children...

Topics

Adult
Child
Humans
ARNTL Transcription Factors
Cross-Sectional Studies
Diabetes Mellitus, Type 2
Fasting
Glucose
Obesity
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36732647
DOI: 10.1038/s41390-023-02467-8
PMCID: PMC10382306

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