Article
Getting too sweet: galectin-1 dysregulation in gestational diabetes mellitus.
Molecular human reproduction - 1 Jul 2014
Blois Sandra M, Gueuvoghlanian-Silva Barbara Y, Tirado-González Irene, Torloni Maria R, Freitag Nancy, Mattar Rosiane, Conrad Melanie L, Unverdorben Laura, Barrientos Gabriela, Knabl Julia, Toldi Gergely, Molvarec Attila, Rose Matthias, Markert Udo R, Jeschke Udo, Daher Silvia
Abstract excerpt
Galectin-1 (gal-1) is a prototype carbohydrate-binding protein, whose dysregulation is associated with adverse pregnancy outcomes such as spontaneous abortion and pre-eclampsia. Furthermore, it is known that faulty gal-1 protein production or gene regulation can be caused by single-nucleotide polymorphisms in the LGALS1 gene. Gestational diabetes mellitus (GDM) is also an adverse pregnancy outcome and the most...
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