Article
Allelic loss mapping and physical delineation of a region harboring a thymic lymphoma suppressor gene on mouse chromosome 16.
Biochemical and biophysical research communications - 23 Mar 2001
Matsuki A, Kosugi-Okano H, Ochiai Y, Kosugi Si, Miyazawa T, Wakabayashi Yi, Hatakeyama K, Niwa O, Kominami R
Abstract excerpt
Our previous mapping of allelic loss in gamma-ray induced thymic lymphomas in F(1) hybrid and backcross mice between BALB/c and MSM strains identified three regions with high frequencies of allelic loss which probably harbor a tumor suppressor gene. One region, Tlsr7, exists near the D16 Mit122 locus on chromosome 16. This study has further localized Tlsr7 by constructing a physical map and scanning a total of...
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