Article
Meiotic mapping of murine chromosome 17: the string of loci around l(17)-2Pas.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 1991
King T R, Dove W F, Guénet J L, Herrmann B G, Shedlovsky A
Abstract excerpt
We describe a genetic analysis of l(17)-2Pas, an embryonic lethal mutation on murine chromosome 17. Males transmitted the l(17)-2 allele to only 38% of their offspring, whereas females transmitted this allele at 50%. Two-point crosses revealed tight linkage between l(17)-2 and brachyury (T), and deletion mapping placed l(17)-2 outside of the hairpin-tail deletion (Thp). To map this mutation more precisely, we...
Topics
- Animals
- Chromosome Mapping
- Crossing Over, Genetic
- Ethylnitrosourea
- Genetic Markers
- H-2 Antigens
- Meiosis
- Mice
- Mutation