Article
Differential gene expression of medullary thyroid carcinoma reveals specific markers associated with genetic conditions.
The American journal of pathology - 1 Feb 2013
Maliszewska Agnieszka, Leandro-Garcia Luis J, Castelblanco Esmeralda, Macià Anna, de Cubas Aguirre, Goméz-López Gonzalo, Inglada-Pérez Lucía, Álvarez-Escolá Cristina, De la Vega Leticia, Letón Rocío, Gómez-Graña Álvaro, Landa Iñigo, Cascón Alberto, Rodríguez-Antona Cristina, Borrego Salud, Zane Mariangela, Schiavi Francesca, Merante-Boschin Isabella, Pelizzo Maria R, Pisano David G, Opocher Giuseppe, Matias-Guiu Xavier, Encinas Mario, Robledo Mercedes
Abstract excerpt
Medullary thyroid carcinoma accounts for 2% to 5% of thyroid malignancies, of which 75% are sporadic and the remaining 25% are hereditary and related to multiple endocrine neoplasia type 2 syndrome. Despite a genotype-phenotype correlation with specific germline RET mutations, knowledge of pathwa...
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