Article

A review of diagnostic approaches to medullary thyroid carcinoma

2017-03-14

Abstract excerpt

Medullary thyroid carcinoma (MTC), occurring sporadically or as an autosomal dominant trait, accounts for 5-10% of all thyroid gland neoplasms. While the sporadic variant originates from somatic rearranged-during-transfection (RET) mutations, the inherited variant is preceded by germ-line mutations of the RET proto-oncogene. Analysis of the transformations of this certain gene is the cornerstone of diagnostic and...

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Literature Corpus work: 60e21423-558b-5911-959e-a88b00e3075a
DOI: 10.1101/116905

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