Article
Opportunities and methods for studying alternative splicing in cancer with RNA-Seq.
Cancer letters - 1 Nov 2013
Feng Huijuan, Qin Zhiyi, Zhang Xuegong
Abstract excerpt
The biogenesis, development and metastases of cancer are associated with many variations in the transcriptome. Alternative splicing of genes is a major post-transcriptional regulation mechanism that is involved in many types of cancer. The next-generation sequencing applied on RNAs (RNA-Seq) provides a new technology for studying transcriptomes. It provides an unprecedented opportunity for quantitatively studying...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
