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Article

Profiles of alternative splicing in colorectal cancer and their clinical significance: A study based on large-scale sequencing data

20 Sept 2018

Abstract excerpt

BACKGROUND: Alternative splicing (AS), as a potent and pervasive mechanism of transcriptional regulatory, expands the genome's coding capacity and involves in the initiation and progression of cancer. Systematic analysis of alternative splicing in colorectal cancer (CRC) is lacking and greatly needed. METHODS: RNA-Seq data and corresponding clinical information of CRC cohort were downloaded from the TCGA data...

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PMID: 30243491
DOI: 10.1016/j.ebiom.2018.09.021

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