Article
A global view of cancer-specific transcript variants by subtractive transcriptome-wide analysis.
PloS one - 1 Jan 2009
He Chunjiang, Zhou Fang, Zuo Zhixiang, Cheng Hanhua, Zhou Rongjia
Abstract excerpt
BACKGROUND: Alternative pre-mRNA splicing (AS) plays a central role in generating complex proteomes and influences development and disease. However, the regulation and etiology of AS in human tumorigenesis is not well understood. METHODOLOGY/PRINCIPAL FINDINGS: A Basic Local Alignment Search Tool database was constructed for the expressed sequence tags (ESTs) from all available databases of human cancer and...
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