Article
RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans.
The Journal of biological chemistry - 25 Jan 2013
LeGendre Jacqueline Baca, Campbell Zachary T, Kroll-Conner Peggy, Anderson Phil, Kimble Judith, Wickens Marvin
Abstract excerpt
The Staufen family consists of proteins that possess double-stranded RNA-binding domains (dsRBDs). Staufen proteins of Drosophila and mammals regulate mRNA localization, translation, and decay. We report analysis of Staufen in Caenorhabditis elegans, which we have designated STAU-1. We focus on its biochemical properties, mRNA targets, and possible role in RNAi. We show that STAU-1 is expressed as mRNA and...
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