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Article

Shared genomic segment analysis with equivalence testing.

Genetic epidemiology - 1 Oct 2020

Horpaopan Sukanya, Fann Cathy S J, Lathrop Mark, Ott Jurg

Abstract excerpt

An important aspect of disease gene mapping is replication, that is, a putative finding in one group of individuals is confirmed in another set of individuals. As it can happen by chance that individuals share an estimated disease position, we developed a statistical approach to determine the p-value for multiple individuals or families to share a possibly small number of candidate susceptibility variants. Here,...

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Share to BRCA1 Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32677112
DOI: 10.1002/gepi.22335
PMCID: PMC7540579

Genes

BRCA1

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