Article
Enhanced genetic maps from family-based disease studies: population-specific comparisons.
BMC medical genetics - 19 Jan 2011
He Chunsheng, Weeks Daniel E, Buyske Steven, Abecasis Goncalo R, Stewart William C, Matise Tara C
Abstract excerpt
BACKGROUND: Accurate genetic maps are required for successful and efficient linkage mapping of disease genes. However, most available genome-wide genetic maps were built using only small collections of pedigrees, and therefore have large sampling errors. A large set of genetic studies genotyped by the NHLBI Mammalian Genotyping Service (MGS) provide appropriate data for generating more accurate maps. RESULTS: We...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.