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Article

EKLF-driven PIT1 expression is critical for mouse erythroid maturation in vivo and in vitro.

Blood - 24 Jan 2013

Forand Anne, Beck Laurent, Leroy Christine, Rousseau Alice, Boitez Valérie, Cohen Isabelle, Courtois Geneviève, Hermine Olivier, Friedlander Gérard

Abstract excerpt

The PIT1/SLC20A1 protein, a well-described sodium/phosphate cotransporter and retrovirus receptor, has been identified recently as a modular of proliferation and apoptosis in vitro. The targeted deletion of the PIT1 gene in mice revealed a lethal phenotype due to severe anemia attributed to defects in liver development. However, the presence of immature erythroid cells associated with impaired maturation of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23190530
DOI: 10.1182/blood-2012-05-427302

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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