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Carotid Intima-Media Thickness: Novel Loci, Sex-Specific Effects, and Genetic Correlations With Obesity and Glucometabolic Traits in UK Biobank.

Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2020

Strawbridge Rona J, Ward Joey, Bailey Mark E S, Cullen Breda, Ferguson Amy, Graham Nicholas, Johnston Keira J A, Lyall Laura M, Pearsall Robert, Pell Jill, Shaw Richard J, Tank Rachana, Lyall Donald M, Smith Daniel J

Abstract excerpt

OBJECTIVE: Atherosclerosis is the underlying cause of most cardiovascular disease, but mechanisms underlying atherosclerosis are incompletely understood. Ultrasound measurement of the carotid intima-media thickness (cIMT) can be used to measure vascular remodeling, which is indicative of atherosclerosis. Genome-wide association studies have identified many genetic loci associated with cIMT, but heterogeneity of...

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Identifiers

PMID: 31801372
DOI: 10.1161/ATVBAHA.119.313226
PMCID: PMC6975521

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Carotid Intima-Media Thickness: Novel Loci, Sex-Specific Effects, and Genetic Correlations With Obesity and Glucometabolic Traits in UK Biobank.PMID 31801372Read ↗

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