Article
Sex-Specific Genetic Variants are Associated With Coronary Endothelial Dysfunction.
Journal of the American Heart Association - 18 Apr 2016
Yoshino Satoshi, Cilluffo Rebecca, Prasad Megha, Best Patricia J M, Atkinson Elizabeth J, Aoki Tatsuo, Cunningham Julie M, de Andrade Mariza, Lerman Lilach O, Lerman Amir
Abstract excerpt
BACKGROUND: Endothelial dysfunction is an early stage of atherosclerosis. Single-nucleotide polymorphisms (SNPs) have been associated with vascular dysfunction, cardiac events, and coronary artery remodeling. We aimed to detect SNPs associated with endothelial dysfunction and determine whether these associations are sex specific. METHODS AND RESULTS: Six hundred forty-three subjects without significant...
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