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Article

Genetic variation in a hsa-let-7 binding site in RAD52 is associated with breast cancer susceptibility.

Carcinogenesis - 1 Mar 2013

Jiang Yue, Qin Zhenzhen, Hu Zhibin, Guan Xiaoxiang, Wang Yanru, He Yisha, Xue Jialei, Liu Xiao'an, Chen Jiaping, Dai Juncheng, Jin Guangfu, Ma Hongxia, Wang Shui, Shen Hongbing

Abstract excerpt

Genetic variants may influence miRNA-mRNA interaction through modulate binding affinity, creating or destroying miRNA-binding sites. Twenty-four single nucleotide polymorphisms (SNPs) that were predicted to affect the binding affinity of breast cancer-related miRNAs to 3'-untranslated regions (UTR) of known genes were genotyped in 878 breast cancer cases and 900 controls in Chinese women. Three promising SNPs...

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Share to Rad52 DNA Repair and Recombination Protein
Share to 3' Untranslated Regions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Binding Sites

Share to Breast Neoplasms

Share to Gene Expression Regulation, Neoplastic

Share to MicroRNAs

Share to RNA Interference

Source

Identifiers

PMID: 23188672
DOI: 10.1093/carcin/bgs373

Genes

RAD52

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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