Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphism rs4919510:C>G in mature sequence of human microRNA-608 contributes to the risk of HER2-positive breast cancer but not other subtypes.

PloS one - 1 Jan 2012

Huang A-Ji, Yu Ke-Da, Li Jing, Fan Lei, Shao Zhi-Ming

Abstract excerpt

BACKGROUND: A few polymorphisms are located in the mature microRNA sequences. Such polymorphisms could directly affect the binding of microRNA to hundreds of target mRNAs. It remains unknown whether rs4919510:C>G located in the mature miR-608 alters breast cancer susceptibility. METHODS: The association of rs4919510:C>G with risk and pathologic features of breast cancer were investigated in two independent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Breast Neoplasms

Share to DNA-Binding Proteins

Share to Genetic Association Studies

Share to Heat Shock Transcription Factors

Share to Logistic Models

Share to MicroRNAs

Share to Neoplasms, Hormone-Dependent

Share to Receptor, ErbB-2

Source

Open in PubMed Open full text

Identifiers

PMID: 22586447
DOI: 10.1371/journal.pone.0035252
PMCID: PMC3346742

Genes

HSF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphism rs4919510:C>G in mature sequence of human microRNA-608 contributes to the risk of HER2-positive breast cancer but not other subtypes.PMID 22586447Read ↗

Association of miR-608 rs4919510 polymorphism and cancer risk: a meta-analysis based on 13,664 subjects.Semantic proximity Read ↗

miR-559 polymorphism rs58450758 is linked to breast cancer.Semantic proximity Read ↗

Association between MIR499A rs3746444 polymorphism and breast cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

The association between rs1972820 and the risk of breast cancer in Isfahan population.Semantic proximity Read ↗

miR-608 rs4919510 C>G polymorphism decreased the risk of breast cancer in an Iranian subpopulation.Semantic proximity Read ↗

Hsa-miR-499 polymorphism (rs3746444) and cancer risk: a meta-analysis of 17 case-control studies.Semantic proximity Read ↗

The miR526b-5p-Related Single Nucleotide Polymorphisms, rs72618599, Located in 3'-UTR of TCF3 Gene, is Associated with the Risk of Breast and Gastric CancersSemantic proximity Read ↗

The role of microRNA-608 polymorphism on the susceptibility and survival of cancer: a meta-analysis.Semantic proximity Read ↗

LncRNA HAR1A in triple-negative breast cancer: mechanisms and the role of polymorphism rs 6089838 in susceptibility.Semantic proximity Read ↗

Five Common Functional Polymorphisms in microRNAs and Susceptibility to Breast Cancer: An Updated Meta-Analysis.Semantic proximity Read ↗

A genetic variant in the pre-miR-27a oncogene is associated with a reduced familial breast cancer risk.Semantic proximity Read ↗

Evaluation the susceptibility of five polymorphisms in microRNA-binding sites to female breast cancer risk in Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.