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Analyzing 395,793 samples shows significant association between rs999737 polymorphism and breast cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jun 2014

Dong Haiying, Gao Zhiying, Li Chengchong, Wang Junping, Jin Ming, Rong Hua, Niu Yingcai, Liu Jicheng

Abstract excerpt

Large-scale genome-wide association studies (GWAS) have been conducted and reported the association between rs999737 polymorphism at 14q24.1 (RAD51L1) and breast cancer risk. Following studies investigated rs999737 polymorphism in European and Asian populations. However, some of these studies reported weak and no significant association. Here, we reevaluated this association using large-scale samples from...

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PMID: 24729084
DOI: 10.1007/s13277-014-1805-4

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