Article
Toll-Like Receptors 2 and 4 Polymorphisms in Age-Related Macular Degeneration.
Current eye research - 1 Jun 2016
Güven Mehmet, Batar Bahadır, Mutlu Tuba, Bostancı Merve, Mete Meltem, Aras Cengiz, Ünal Mustafa
Abstract excerpt
PURPOSE: Age-related macular degeneration (AMD) is a complex disorder with multifactorial etiology, caused by a combination of genetic and environmental factors. Innate immunity appears to play a key role in the pathogenesis of AMD. The purpose of this study was to determine whether common variation in the human toll-like receptors (TLRs) 2 and 4 alters the risk of AMD. PATIENTS AND METHODS: A total of 183...
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