Article
Common genetic variation near the connexin-43 gene is associated with resting heart rate in African Americans: a genome-wide association study of 13,372 participants.
Heart rhythm - 1 Mar 2013
Deo R, Nalls M A, Avery C L, Smith J G, Evans D S, Keller M F, Butler A M, Buxbaum S G, Li G, Miguel Quibrera P, Smith E N, Tanaka T, Akylbekova E L, Alonso A, Arking D E, Benjamin E J, Berenson G S, Bis J C, Chen L Y, Chen W, Cummings S R, Ellinor P T, Evans M K, Ferrucci L, Fox E R, Heckbert S R, Heiss G, Hsueh W C, Kerr K F, Limacher M C, Liu Y, Lubitz S A, Magnani J W, Mehra R, Marcus G M, Murray S S, Newman A B, Njajou O, North K E, Paltoo D N, Psaty B M, Redline S S, Reiner A P, Robinson J G, Rotter J I, Samdarshi T E, Schnabel R B, Schork N J, Singleton A B, Siscovick D, Soliman E Z, Sotoodehnia N, Srinivasan S R, Taylor H A, Trevisan M, Zhang Z, Zonderman A B, Newton-Cheh C, Whitsel E A
Abstract excerpt
BACKGROUND: Genome-wide association studies have identified several genetic loci associated with variation in resting heart rate in European and Asian populations. No study has evaluated genetic variants associated with heart rate in African Americans. OBJECTIVE: To identify novel genetic variants associated with resting heart rate in African Americans. METHODS: Ten cohort studies participating in the...
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