Article
The relationship between changes in functional cardiac parameters following anthracycline therapy and carbonyl reductase 3 and glutathione S transferase Pi polymorphisms.
Journal of chemotherapy (Florence, Italy) - 1 Oct 2012
Volkan-Salanci Bilge, Aksoy Hakan, Kiratli Pınar Özgen, Tülümen Erol, Güler Nilüfer, Öksüzoglu Berna, Tokgözoğlu Lale, Erbaş Belkıs, Alikaşifoğlu Mehmet
Abstract excerpt
The aim of this prospective clinical study is to evaluate the relationship between changes in functional cardiac parameters following anthracycline therapy and carbonyl reductase 3 (CBR3p.V244M) and glutathione S transferase Pi (GSTP1p.I105V) polymorphisms. Seventy patients with normal cardiac function and no history of cardiac disease scheduled to undergo anthracycline chemotherapy were included in the study....
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