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Article

Clinical and genetic risk factors for anthracycline‑induced cardiotoxicity in Chinese early‑stage breast cancer patients: a candidate gene study.

Future oncology (London, England) - 1 Aug 2026

Xu Shan, Yang Hao, Hu Nan

Abstract excerpt

PURPOSE: This study aimed to clarify the incidence of anthracycline-induced cardiotoxicity (ACT) and identify its clinical and candidate genetic risk factors in Chinese early-stage breast cancer patients, so as to provide evidence for clinical risk assessment and individualized cardiac protection. METHODS: This study included 119 patients who received anthracycline-based chemotherapy. Cardiac function was...

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Share to Anthracyclines
Share to ATP Binding Cassette Transporter, Subfamily B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to East Asian People

Share to Glutathione S-Transferase pi

Share to Membrane Transport Proteins

Share to Multidrug Resistance-Associated Protein 2

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Source

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Identifiers

PMID: 42549829
DOI: 10.1080/14796694.2026.2713355
PMCID: PMC13540168

Genes

ABCB1
ABCC2
CBR3
GSTP1
SLC28A3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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