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RS4673 and pon1 level in blood plasma - new prospects in prediction and early diagnostics of anthracycline-mediated cardiotoxicity.

Klinicheskaia laboratornaia diagnostika - 23 Feb 2022

Gvaldin D Yu, Timoshkina N N, Vashchenko L N, Novikova I A, Vladimirova L Yu, Storozhakova A E, Sagakyants A B

Abstract excerpt

The purpose of this study was to research the effectiveness of molecular genetic tests based on the determination of the rs4673 CYBA polymorphism (c.242C>T) and the level of paraoxonase 1 (PON1) in the blood plasma of patients with breast cancer (BC) for predicting and diagnosing anthracycline-mediated cardiotoxicity (AMC). The genotyping of rs4673 CYBA (c.242C>T) and the study of the PON1 level in the blood...

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Identifiers

PMID: 35192760
DOI: 10.51620/0869-2084-2022-67-2-123-128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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