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Article

Influence of the polymorphism in candidate genes on late cardiac damage in patients treated due to acute leukemia in childhood.

Leukemia & lymphoma - 1 Oct 2009

Rajić Vladan, Aplenc Richard, Debeljak Marusa, Prestor Veronika Velensek, Karas-Kuzelicki Natasa, Mlinaric-Rascan Irena, Jazbec Janez

Abstract excerpt

Anthracyclines have contributed significantly to the increased cure rate in pediatric oncology. Cardiac toxicity is an important late effect after anthracycline treatment and is thought to occur by reactive oxygen species mediated cardiac damage. We hypothesized that deactivating variants of supe...

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Source

Identifiers

PMID: 19863340
DOI: 10.1080/10428190903177212

Genes

CAT
GSTM1
GSTT1
SOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19863340-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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