Article
Association studies of several cholesterol-related genes (ABCA1, CETP and LIPC) with serum lipids and risk of Alzheimer's disease.
Lipids in health and disease - 26 Nov 2012
Xiao Zhijie, Wang Juan, Chen Weirong, Wang Peng, Zeng Houlin, Chen Weixi
Abstract excerpt
OBJECTIVES: Accumulating evidence suggested that dysregulation of cholesterol homeostasis might be a major etiologic factor in initiating and promoting neurodegeneration in Alzheimer's disease (AD). ATP-binding cassette transporter A1 (ABCA1), hepatic lipase (HL, coding genes named LIPC) and cholesteryl ester transfer protein (CETP) are important components of high-density lipoprotein (HDL) metabolism and reverse...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
