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Article

Association of genetic variants of ABCA1 with susceptibility to dementia: (SADEM study).

Metabolic brain disease - 1 Aug 2020

Teresa Juárez-Cedillo, Fernado Calzada, Nancy Martínez-Rodríguez, Gilberto Vargas-Alarcón, Alberto Cruz-Rocha, Roberto Robles-Ramirez

Abstract excerpt

Because of the importance of cholesterol metabolism in the physiopathogenesis of dementia, and knowing the function of ATP-binding cassette A1 transporter (ABCA1) as a cholesterol flow pump at the cellular and cerebral level, it has been noted that the ABCA1 gene may be a good candidate for disease study. In order to evaluate the relationship between ABCA1 genetic variants and the risk of Alzheimer's disease and...

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PMID: 32447570
DOI: 10.1007/s11011-020-00577-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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